Sudden Cardiac Death Prevention in Patients with Ischemic Heart Disease—Beyond the Ejection Fraction

Sudden cardiac death (SCD) in patients with ischemic heart disease remains a leading cause of death. Prediction who is at risk based on the left ventricular ejection fraction (EF). However, majority victims SCD have normal EF, and implanted an implantable cardioverter- defibrillator their EF are never treated by device. Several parameters could allow better prediction SCD. signs ECG Periodic Repolarization Dynamics been associated increased risk. Elevated serum biomarkers such as pro-B type natriuretic peptides soluble suppression tumorigenicity 2 protein (sST2) predictive On echocardiogram, global longitudinal strain, speckle tracking relative wall thickness implicated. Programmed stimulation studies magnetic resonance promising modalities that be further investigated. In conclusion, imperfect tool for predicting Using reviewed, model created